0去购物车结算
购物车中还没有商品,赶紧选购吧!
当前位置: 图书分类 > 化学 > 有机化学 > 高等有机化学——反应与合成(第5版)

相同语种的商品

浏览历史

高等有机化学——反应与合成(第5版)


联系编辑
 
标题:
 
内容:
 
联系方式:
 
  
高等有机化学——反应与合成(第5版)
  • 书号:9787030238580
    作者:Carey, Francis A., Sundberg, Richard J.
  • 外文书名:Advanced Organic Chemistry Part B:Reactions and Synthesis
  • 丛书名:国外化学名著系列(影印版)
  • 装帧:平装
    开本:B5
  • 页数:1352
    字数:1600
    语种:英文
  • 出版社:科学出版社
    出版时间:2016-01-29
  • 所属分类:O62 有机化学
  • 定价: ¥160.00元
    售价: ¥128.00元
  • 图书介质:
    纸质书

  • 购买数量: 件  缺货,请选择其他介质图书!
  • 商品总价:

相同系列
全选

内容介绍

样章试读

用户评论

全部咨询

  自1977年面世以来,《高级有机化学》作为学科首选教材的地位一直没有动摇过,广泛地覆盖了有机化合物的结构、反应活性及合成。她的第五版相对2001年出版的第四版进行了大幅度的修订,更新了学科发展的相关资料,内容组织更加清晰明朗,特别是计算化学部分。通过控制反应而得到特定的合成是有机合成的全部目标。Part B在不同反应类型的基础上详尽地描述了最常见的和最有用的合成反应。每章后附有习题精选及解答习题的推荐参考文献。
  本书可供有机化学、药物化学和生物化学等专业的高年级本科生、研究生以及相关领域的科研人员参考。
样章试读
  • wx_结晶紫63071 ( 2021-04-08 14:20:31 )

总计 1 个记录,共 1 页。 第一页 上一页 下一页 最末页

全部咨询(共0条问答)

  • 暂时还没有任何用户咨询内容
总计 0 个记录,共 1 页。 第一页 上一页 下一页 最末页
用户名: 匿名用户
E-mail:
咨询内容:

目录

  • Preface
    Acknowledgment and Personal Statemrnt
    Introduction
    Chapter 1. Alkylation of Enolates and Other Carbon Nucleophiles
    Introduction
    1.1. Generation and Properties of Enolates and Other Stabilized Carbanions
    1.1.1. Generation of Enolates by Deprotonation
    1.1.2. Regioselectivity and Stereoselectivity in Enolate Formation from Ketones and Esters
    1.1.3. Other Means of Generating Enolates
    1.1.4. Solvent Effects on Enolate Structure and Reactivity
    1.2. Alkylation of Enolates
    1.2.1. Alkylation of Highly Stabilized Enolates
    1.2.2. Alkylation of Ketone Enolates
    1.2.3. Alkylation of Aldehydes,Esters,Carboxylic Acids,Amides,and Nitriles
    1.2.4. Generation and Alkylation of Dianions
    1.2.5. Intramolecular Alkylation of Enolates
    1.2.6. Control of Enantioselectivity in Alkylation Reactions
    1.3. The Nitrogen Analogs of Enols and Enolates:Enamines and Imine Anions
    General References
    Problems
    Chapter 2. Reactions of Carbon Nucleophiles with Carbonyl Compounds
    Introduction
    2.1. Aldol Addition and Condensation Reactions
    2.1.1. The General Mechanism
    2.1.2. Control of Regio- and Stereoselectivity of Aldol Reactions of Aldehydes and Ketones
    2.1.3. Aldol Addition Reactions of Enolates of Esters and Other Carbonyl Derivatives
    2.1.4. The Mukaiyama Aldol Reaction
    2.1.5. Control of Facial Selectivity in Aldol and Mukaiyama Aldol Reactions
    2.1.6. Intramolecular Aldol Reactions and the Robinson Annulation
    2.2. Addition Reactions of Imines and Iminium Ions
    2.2.1. The Mannich Reaction
    2.2.2. Additions to N-Acyl Iminium Ions
    2.2.3. Amine-Catalyzed Condensation Reactions
    2.3. Acylation of Carbon Nucleophiles
    2.3.1. Claisen and Dieckmann Condensation Reactions
    2.3.2. Acylation of Enolates and Other Carbon Nucleophiles
    2.4. Olefination Reactions of Stabilized Carbon Nucleophiles
    2.4.1. The Wittig and Related Reactions of Phosphorus-Stabilized Carbon Nucleophiles
    2.4.2. Reactions of α-Trimethylsilylcarbanions with Carbonyl Compounds
    2.4.3. The Julia Olefination Reaction
    2.5. Reactions Proceeding by Addition-Cyclization
    2.5.1. Sulfur Ylides and Related Nucleophiles
    2.5.2. Nucleophilic Addition-Cyclization of α-Haloesters
    2.6. Conjugate Addition by Carbon Nucleophiles
    2.6.1. Conjugate Addition of Enolates
    2.6.2. Conjugate Addition with Tandem Alkylation
    2.6.3. Conjugate Addition by Enolate Equivalents
    2.6.4. Control of Facial Selectivity in Conjugate Addition Reactions
    2.6.5. Conjugate Addition of Organometallic Reagents
    2.6.6. Conjugate Addition of Cyanide Ion
    General References
    Problems
    Chapter 3. Functional Group Interconversion by Substitution,Including Protection and Deproteetion
    Introduction
    3.1. Conversion of Alcohols to Alkylating Agents
    3.1.1. Sulfonate Esters
    3.1.2. Halides
    3.2. Introduction of Functional Groups by Nucleophilic Substitution at Saturated Carbon
    3.2.1. General Solvent Effects
    3.2.2. Nitriles
    3.2.3. Oxygen Nucleophiles
    3.2.4. Nitrogen Nucleophiles
    3.2.5. Sulfur Nucleophiles
    3.2.6. Phosphorus Nucleophiles
    3.2.7. Summary of Nucleophilic Substitution at Saturated Carbon
    3.3. Cleavage of Carbon-Oxygen Bonds in Ethers and Esters
    3.4. Interconversion of Carboxylic Acid Derivatives
    3.4.1. Acylation of Alcohols
    3.4.2. Fischer Esterification
    3.4.3. Preparation of Amides
    3.5. Installation and Removal of Protective Groups
    3.5.1. Hydroxy-Protecting Groups
    3.5.2. Amino-Protecting Groups
    3.5.3. Carbonyl-Protecting Groups
    3.5.4. Carboxylic Acid-Protecting Groups
    Problems
    Chapter 4. Electrophilic Additions to Carbon-Carbon Multiple Bonds
    Introduction
    4.1. Electrophilic Addition to Alkenes
    4.1.1. Addition of Hydrogen Halides
    4.1.2. Hydration and Other Acid-Catalyzed Additions of Oxygen Nucleophiles
    4.1.3. Oxymercuration-Reduction
    4.1.4. Addition of Halogens to Alkenes
    4.1.5. Addition of Other Electrophilic Reagents
    4.1.6. Addition Reactions with Electrophilic Sulfur and Selenium Reagents
    4.2. Electrophilic Cyclization
    4.2.1. Halocyclization
    4.2.2. Sulfenylcyclization and Selenenylcyclization
    4.2.3. Cyclization by Mercuric Ion
    4.3. Electrophilic Substitution α to Carbonyl Groups
    4.3.1. Halogenation α to Carbonyl Groups
    4.3.2. Sulfenylation and Selenenylation α to Carbonyl Groups
    4.4. Additions to Allenes and Alkynes
    4.5. Addition at Double Bonds via Organoborane Intermediates
    4.5.1. Hydroboration
    4.5.2. Reactions of Organoboranes
    4.5.3. Enantioselective Hydroboration
    4.5.4. Hydroboration of Alkynes
    4.6. Hydroalumination, Carboalumination, Hydrozirconation,and Related Reactions
    General References
    Problems
    Chapter 5. Reduction of Carbon-Carbon Multiple Bonds,Carbonyl Groups,and Other Functional Groups
    Introduction
    5.1. Addition of Hydrogen at Carbon-Carbon Multiple Bonds
    5.1.1. Hydrogenation Using Heterogeneous Catalysts
    5.1.2. Hydrogenation Using Homogeneous Catalysts
    5.1.3. Enantioselective Hydrogenation
    5.1.4. Partial Reduction of Alkynes
    5.1.5. Hydrogen Transfer from Diimide
    5.2. Catalytic Hydrogenation of Carbonyl and Other Functional Groups
    5.3. Group III Hydride-Donor Reagents
    5.3.1. Comparative Reactivity of Common Hydride Donor Reagents
    5.3.2. Stereoselectivity of Hydride Reduction
    5.3.3. Enantioselective Reduction of Carbonyl Compounds
    5.3.4. Reduction of Other Functional Groups by Hydride Donors
    5.4. Group IV Hydride Donors
    5.4.1. Reactions Involving Silicon Hydrides
    5.4.2. Hydride Transfer from Carbon
    5.5. Reduction Reactions Involving Hydrogen Atom Donors
    5.6. Dissolving-Metal Reductions
    5.6.1. Addition of Hydrogen
    5.6.2. Reductive Removal of Functional Groups
    5.6.3. Reductive Coupling of Carbonyl Compounds
    5.7. Reductive Deoxygenation of Carbonyl Groups
    5.7.1. Reductive Deoxygenation of Carbonyl Groups to Methylene
    5.7.2. Reduction of Carbonyl Compounds to Alkenes
    5.8. Reductive Elimination and Fragmentation
    Problems
    Chapter 6. Concerted Cyeloadditions,Unimoleeular Rearrangements,and Thermal Eliminations
    Introduction
    6.1. Diels-Alder Reactions
    6.1.1. The Diels-Alder Reaction: General Features
    6.1.2. Substituent Effects on the Diels-Alder Reaction
    6.1.3. Lewis Acid Catalysis of the Diels-Alder Reaction
    6.1.4. The Scope and Synthetic Applications of the Diels-Alder Reaction
    6.1.5. Diastereoselective Diels-Alder Reactions Using Chiral Auxiliaries
    6.1.6. Enantioselective Catalysts for Diels-Alder Reactions
    6.1.7. Intramolecular Diels-Alder Reactions
    6.2. 1,3-Dipolar Cycloaddition Reactions
    6.2.1. Regioselectivity and Stereochemistry
    6.2.2. Synthetic Applications of Dipolar Cycloadditions
    6.2.3. Catalysis of 1,3-Dipolar Cycloaddition Reactions
    6.3. [2 + 2] Cycloadditions and Related Reactions Leading to Cyclobutanes
    6.3.1. Cycloaddition Reactions of Ketenes and Alkenes
    6.3.2. Photochemical Cycloaddition Reactions
    6.4. [3,3]-Sigmatropic Rearrangements
    6.4.1. Cope Rearrangements
    6.4.2. Claisen and Modified Claisen Rearrangements
    6.5. [2,3]-Sigmatropic Rearrangements
    6.5.1. Rearrangement of Allylic Sulfoxides, Selenoxides,and Amine Oxides
    6.5.2. Rearrangement of Allylic Sulfonium and Ammonium Ylides
    6.5.3. Anionic Wittig and Aza-Wittig Rearrangements
    6.6. Unimolecular Thermal Elimination Reactions
    6.6.1. Cheletropic Elimination
    6.6.2. Decomposition of Cyclic Azo Compounds
    6.6.3. [3-Eliminations Involving Cyclic Transition Structures
    Problems
    Chapter 7. Organometallie Compounds of Group I and II Metals
    Introduction
    7.1. Preparation and Properties of Organomagnesium and Organolithium Reagents
    7.1.1. Preparation and Properties of Organomagnesium Reagents
    7.1.2. Preparation and Properties of Organolithium Compounds
    7.2. Reactions of Organomagnesium and Organolithium Compounds
    7.2.1. Reactions with Alkylating Agents
    7.2.2. Reactions with Carbonyl Compounds
    7.3. Organometallic Compounds of Group IIB and IIIB Metals
    7.3.1. Organozinc Compounds
    7.3.2. Organocadmium Compounds
    7.3.3. Organomercury Compounds
    7.3.4. Organoindium Reagents
    7.4. Organolanthanide Reagents
    General References
    Problems
    Chapter 8. Reactions Involving Transition Metals
    Introduction
    8.1. Organocopper Intermediates
    8.1.1. Preparation and Structure of Organocopper Reagents
    8.1.2. Reactions Involving Organocopper Reagents and Intermediates
    8.2. Reactions Involving Organopalladium Intermediates
    8.2.1. Palladium-Catalyzed Nucleophilic Addition and Substitution
    8.2.2. The Heck Reaction
    8.2.3. Palladium-Catalyzed Cross Coupling
    8.2.4. Carbonylation Reactions
    8.3. Reactions Involving Other Transition Metals
    8.3.1. Organonickel Compounds
    8.3.2. Reactions Involving Rhodium and Cobalt
    8.4. The Olefin Metathesis Reaction
    8.5. Organometallic Compounds with w-Bonding
    General References
    Problems
    Chapter 9. Carbon-Carbon Bond-Forming Reactions of Compounds of Boron, Silicon, and Tin
    Introduction
    9.1. Organoboron Compounds
    9.1.1. Synthesis of Organoboranes
    9.1.2. Carbonylation and Other One-Carbon Homologation Reactions
    9.1.3. Homologation via α-Halo Enolates
    9.1.4. Stereoselective Alkene Synthesis
    9.1.5. Nucleophilic Addition of Allylic Groups from Boron Compounds
    9.2. Organosilicon Compounds
    9.2.1. Synthesis of Organosilanes
    9.2.2. General Features of Carbon-Carbon Bond-Forming Reactions of Organosilicon Compounds
    9.2.3. Addition Reactions with Aldehydes and Ketones
    9.2.4. Reaction with Iminium Ions
    9.2.5. Acylation Reactions
    9.2.6. Conjugate Addition Reactions
    9.3. Organotin Compounds
    9.3.1. Synthesis of Organostannanes
    9.3.2. Carbon-Carbon Bond-Forming Reactions
    9.4. Summary of Stereoselectivity Patterns
    General References
    Problems
    Chapter 10. Reactions Involving Carboeations,Carbenes,and Radicals as Reactive Intermediates
    Introduction
    10.1. Reactions and Rearrangement Involving Carbocation Intermediates
    10.1.1. Carbon-Carbon Bond Formation Involving Carbocations
    10.1.2. Rearrangement of Carbocations
    10.1.3. Related Rearrangements
    10.1.4. Fragmentation Reactions
    10.2. Reactions Involving Carbenes and Related Intermediates
    10.2.1. Reactivity of Carbenes
    10.2.2. Generation of Carbenes
    10.2.3. Addition Reactions
    10.2.4. Insertion Reactions
    10.2.5. Generation and Reactions of Ylides by Carbenoid Decomposition
    10.2.6. Rearrangement Reactions
    10.2.7. Related Reactions
    10.2.8. Nitrenes and Related Intermediates
    10.2.9. Rearrangements to Electron-Deficient Nitrogen
    10.3. Reactions Involving Free Radical Intermediates
    10.3.1. Sources of Radical Intermediates
    10.3.2. Addition Reactions of Radicals with Substituted Alkenes
    10.3.3. Cyclization of Free Radical Intermediates
    10.3.4. Additions to C=N Double Bonds
    10.3.5. Tandem Radical Cyclizations and Alkylations
    10.3.6. Fragmentation and Rearrangement Reactions
    10.3.7. Intramolecular Functionalization by Radical Reactions
    Problems
    Chapter 11. Arornatie Substitution Reactions
    Introduction
    11.1. Electrophilic Aromatic Substitution
    11.1.1. Nitration
    11.1.2. Halogenation
    11.1.3. Friedel-Crafts Alkylation
    11.1.4. Friedel-Crafts Acylation
    11.1.5. Related Alkylation and Acylation Reactions
    11.1.6. Electrophilic Metallation
    11.2. Nucleophilic Aromatic Substitution
    11.2.1. Aryl Diazonium Ions as Synthetic Intermediates
    11.2.2. Substitution by the Addition-Elimination Mechanism
    11.2.3. Substitution by the Elimination-Addition Mechanism
    11.3. Transition Metal-Catalyzed Aromatic Substitution Reactions
    11.3.1. Copper-Catalyzed Reactions
    11.3.2. Palladium-Catalyzed Reactions
    11.4. Aromatic Substitution Reactions Involving Radical Intermediates
    11.4.1. Aromatic Radical Substitution
    11.4.2. Substitution by the SRN1 Mechanism
    Problems
    Chapter 12. Oxidations
    Introduction
    12.1. Oxidation of Alcohols to Aldehydes, Ketones, or Carboxylic Acids
    12.1.1. Transition Metal Oxidants
    12.1.2. Other Oxidants
    12.2. Addition of Oxygen at Carbon-Carbon Double Bonds
    12.2.1. Transition Metal Oxidants
    12.2.2. Epoxides from Alkenes and Peroxidic Reagents
    12.2.3. Subsequent Transformations of Epoxides
    12.3. Allylic Oxidation
    12.3.1. Transition Metal Oxidants
    12.3.2. Reaction of Alkenes with Singlet Oxygen
    12.3.3. Other Oxidants
    12.4. Oxidative Cleavage of Carbon-Carbon Double Bonds
    12.4.1. Transition Metal Oxidants
    12.4.2. Ozonolysis
    12.5. Oxidation of Ketones and Aldehydes
    12.5.1. Transition Metal Oxidants
    12.5.2. Oxidation of Ketones and Aldehydes by Oxygen and Peroxidic Compounds
    12.5.3. Oxidation with Other Reagents
    12.6. Selective Oxidative Cleavages at Functional Groups
    12.6.1. Cleavage of Glycols
    12.6.2. Oxidative Decarboxylation
    12.7. Oxidations at Unfunctionalized Carbon
    Problems
    Chapter 13. Multistep Syntheses
    Introduction
    13.1. Synthetic Analysis and Planning
    13.1.1. Retrosynthetic Analysis
    13.1.2. Synthetic Equivalent Groups
    13.1.3. Control of Stereochemistry
    13.2. Illustrative Syntheses
    13.2.1. Juvabione
    13.2.2. Longifolene
    13.2.3. Prelog-Djerassi Lactone
    13.2.4. Baccatin III and Taxol
    13.2.5. Epothilone A
    13.2.6. Discodermolide
    13.3. Solid Phase Synthesis
    13.3.1. Solid Phase Polypeptide Synthesis
    13.3.2. Solid Phase Synthesis of Oligonucleotides
    13.4. Combinatorial Synthesis
    General References
    Problems
    References
    Index
帮助中心
公司简介
联系我们
常见问题
新手上路
发票制度
积分说明
购物指南
配送方式
配送时间及费用
配送查询说明
配送范围
快递查询
售后服务
退换货说明
退换货流程
投诉或建议
版权声明
经营资质
营业执照
出版社经营许可证