Note Preface Introduction Chapter 1 Structures and Functions of Proteins 1.1 Amino Acid Composition in Proteins 1.2 Molecular Structures of Proteins 1.3 Structure-Function Relationships of Proteins 1.4 Protein Physicochemical Properties and Principles of Purification 1.5 Proteome and Proteomics Summary Chapter 2 Structures and Functions of Nucleic Acids 2.1 The Structural Units of Nucleic Acids—Nucleotides 2.2 Structures and Functions of DNA 2.3 Structures and Functions of RNA 2.4 Properties of Nucleic Acids 2.5 Nucleases 2.6 Genomics and the Human Genome Project Summary Chapter 3 Enzymes 3.1 Structure and Function of Enzymes 3.2 Properties and Catalytic Mechanisms of Enzymes 3.3 Kinetics of Enzyme-Catalyzed Reactions 3.4 Regulation of Enzyme Activity 3.5 Nomenclature and Classification of Enzymes 3.6 Clinical Applications of Enzymes… Summary Chapter 4 Carbohydrate Metabolism 4.1 Digestion and Absorption of Carbohydrates 4.2 Anaerobic Degradation of Glucose 4.3 Aerobic Oxidation of Glucose 4.4 Glycogen Formation and Degradation 4.5 Gluconeogenesis 4.6 Pentose Phosphate Pathway 4.7 Blood Sugar and Its Regulation Summary Chapter 5 Lipid Metabolism 5.1 Fatty Acids and Derivatives of Polyunsaturated Fatty Acids 5.2 Digestion and Absorption of Lipids 5.3 Metabolism of Fats 5.4 Metabolism of Phospholipids 5.5 Metabolism of Cholesterol 5.6 Metabolism of Plasma Lipoproteins Summary Chapter 6 Biological Oxidation 6.1 Electron Transport Chain 6.2 Oxidative Phosphorylation 6.3 ATP and the Other High Energy Compounds 6.4 Selective Transport across the Inner Mitochondrial Membrane 6.5 Other Biological Oxidations Summary Chapter 7 Protein Catabolism 7.1 Nutritional Roles of Dietary Proteins 7.2 Digestion，Absorption and Putrefaction of Proteins 7.3 Degradation of Proteins in Cells 7.4 General Catabolism of Amino Acids 7.5 Metabolism of Ammonia 7.6 Individual Amino Acid Catabolism Summary Chapter 8 Nucleotide Metabolism 8.1 Biological and Medical Functions of Nucleotides 8.2 Degradation of Nucleic Acids 8.3 Metabolism of Purine Nucleotides 8.4 Metabolism of Pyrimidine Nucleotides 8.5 Deoxyribonucleotide Biosynthesis 8.6 Biosynthesis of Nucleoside Diphosphates and Nucleosides Triphosphates 8.7 Dysmetabolism of Nucleotides and Antimetabolites Summary Chapter 9 Regulation of Metabolism 9.1 Metabolic Regulation at Cell Level 9.2 Metabolic Regulation at Hormone Level 9.3 Regulation of Metabolism at Integral Level Summary Chapter 10 DNA Biosynthesis 10.1 General Features of DNA Replication 10.2 Eukaryotic DNA Replication 10.3 Prokaryotic DNA Replication 10.4 Other Modes of DNA Replication 10.5 DNA Damage and Repair Summary Chapter 11 RNA Biosynthesis 11.1 Overview of Transcription 11.2 Transcription in Eukaryotes 11.3 Processing of Eukaryotic RNA 11.4 Transcription in Prokaryotes 11.5 RNA-Dependent RNA Synthesis Summary Chapter 12 Protein Biosynthesis 12.1 Machinery Involved in Translation 12.2 Amino Acid Activation 12.3 Protein Biosynthesis Journey 12.4 Protein Posttranslational Modifications and Targeting 12.5 Clinical Correlation of Protein Biosynthesis Summary Chapter 13 Regulation of Gene Expression 13.1 General Characteristics of Gene Expression 13.2 Regulation of Gene Expression in Prokaryotes 13.3 Regulation of Gene Expression in Eukaryotes Summary Chapter 14 DNA Technology 14.1 Genetic Engineering 14.2 Molecular Hybridization 14.3 Polymerase Chain Reaction 14.4 DNA Sequencing 14.5 Transgenesis，Animal Cloning and Gene Knockout Technologies 14.6 Gene Diagnosis 14.7 Gene Therapy Summary Chapter 15 Biomembranes 15.1 Molecular Compositions of Biomembranes 15.2 Structures of Biomembranes 15.3 Transportation Functions of Biomembranes 15.4 Biomembrane and Medicine Summary Chapter 16 Glycoproteins，Proteoglycans and Extracellular Matrix 16.1 Structures and Functions of Glycoproteins 16.2 Structures and Functions of Proteoglycans 16.3 Extracellular Matrix Summary Chapter 17 Signal Transduction 17.1 Signal Molecules 17.2 Receptors 17.3 Signal Transduction Pathways 17.4 Interrelationship between Signal Transduction Pathways 17.5 Signal Transduction and Medicine Summary Chapter 18 Oncogenes，Tumor Suppressor Genes and Growth Factors 18.1 Oncogenes 18.2 Tumor Suppressor Genes 18.3 Growth Factors Summary Chapter 19 Blood Biochemistry 19.1 Plasma Proteins 19.2 Blood Coagulation 19.3 Metabolism of Blood Cells Summary Chapter 20 Liver Biochemistry 20.1 The Role of Liver in Material Metabolism 20.2 Hepatic Biotransformation 20.3 Metabolism of Bile Acids 20.4 Bile Pigment Metabolism and Jaundice Summary Chapter 21 Vitamins and Minerals 21.1 Fat-Soluble Vitamins 21.2 Water-Soluble Vitamins 21.3 Calcium，Phosphorus and Magnesium Metabolism 21.4 Trace Elements Summary Appendix A Greek Alphabets Appendix B Prefixes of System International Unites Appendix C The Numeral Prefix of Chemical Compounds Appendix D Some Common Used Biochemical Abbreviations Appendix E Index Appendix F The Majar References Glossary
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