中文摘要 化学生物学 Enzymatic tools for engineering natural product glycosylation Sophie Blanchard and Jon S Thorson 天然产物糖基化的工具酶 Nucleic acid aptamers and enzymes as sensors Naveen K Navani and Yingfu Li 作为传感器的核酸适配子和酶 Catalytic antibodies and their applications Carl Veith Hanson, Yasuhiro Nishiyama and Sudhir Paul 催化抗体及其应用 The evolution of DNA polymerases with novel activities Allison A Henry and Floyd E Romesberg 新活性DNA聚合酶的人工进化 Understanding enzyme action on immobilised substrates Peter J Halling, Rein V Ulijn and Sabine L Flitsch 酶对固定化底物的作用 Mining genomes and ‘metagenomes’ for novel catalysts Manuel Ferrer, Francisco Martnez-Abarca and Peter N Golyshin 从基因组和“宏基因组”中寻找新型催化剂 Ultra-high-throughput screening based on cell-surface display and fluorescence-activated cell sorting for the identification of novel biocatalysts Stefan Becker, Hans-Ulrich Schmoldt, Thorsten Michael Adams, Susanne Wilhelm and Harald Kolmar 基于细胞表面展示及荧光活化细胞分类的超高通量筛选,寻找新型生物催化剂 Improved β-lactam acylases and their use as industrial biocatalysts Charles F Sio and Wim J Quax 改良的β-内酰胺酰基转移酶及其作为工业生物催化剂的应用 Enzyme catalysed deracemisation and dynamic kinetic resolution reactions Nicholas J Turner 酶催化的去消旋化和动态动力学拆分 Peroxide-utilizing biocatalysts: structural and functional diversity of heme-containing enzymes Isamu Matsunaga and Yoshitsugu Shiro 利用过氧化物的生物催化剂:含有亚铁血红素的酶的结构与功能的多样性 Hydrogenases: active site puzzles and progress Fraser A Armstrong 氢化酶:活性位点之谜与进展 Enantioselective biocatalysis optimized by directed evolution Karl-Erich Jaeger and Thorsren Eggert 通过定向进化优化对映选择性生物催化剂 Evolving haloalkane dehalogenases Dick B Janssen 卤烷烃去卤化酶的人工进化 Harnessing microbial activities for environmental cleanup Frank EöLfler, Elizabeth A Edwards 利用微生物活性进行环境净化 Bioethanol Kevin A Gray, Lishan Zhao and Mark Emptage 生物乙醇 Chemical diversity through biotransformations Michael Müller 生物转化带来的化学多样性 Metabolic engineering of Escherichia coli and Corynebacterium glutamicum for biotechnological production of organic acids and amino acids Volker F Wendisch, Michael Bott and Bernhard J Eikmanns 生产有机酸和氨基酸的大肠杆菌与谷氨酰胺棒状杆菌的代谢工程 Recent advances in oxygenase-catalyzed biotransformations Vlada B Urlacher and Rolf D Schmid 加氧酶催化的生物转化的最新进展 The soil metagenome-a rich resource for the discovery of novel natural products Rolf Daniel 土壤宏基因组-发现新型天然产物的宝库 Biocatalysis in pharmaceutical preparation and alteration Barrie Wilkinson and Brian O Bachmann 药物制备与改造中的生物催化 High-throughput screening of biocatalytic activity: applications in drug discovery R Anand Kumar and Douglas S Clark 生物催化活性的高通量筛选:在药物发现中的应用 High-throughput screens and selections of enzyme-encoding genes Amir Aharoni, Andrew D Griffiths and Dan S Tawfik 酶编码基因的高通量筛选与精选 Predicting enzyme function from protein sequence Jeremy Minshull, Jon E Ness, Claes Gustafsson and Sridhar Govindarajan 从蛋白质序列预测酶功能 Synthesis and modifications of carbohydrates, using biotransformations Alison M Daines, Beatrice A Maltman and Sabine L Flitsch 应用生物转化进行碳水化合物的合成和修饰 Whole organism biocatalysis Takeru Ishige, Kohsuke Honda and Sakayu Shimizu 全生物体生物催化