目录 第一章 中药糖蛋白概述 1 第一节 中药糖蛋白的研究意义 1 第二节 中药糖蛋白的组成、结构 2 第三节 中药糖蛋白代谢 8 第四节 中药糖蛋白生物学功能 11 第二章 中药糖蛋白提取、分离纯化技术 14 第一节 中药糖蛋白提取技术 14 第二节 中药糖蛋白分离纯化技术 16 第三节 亲和色谱在中药糖蛋白分离纯化中的应用 19 第四节 尺寸排阻色谱在中药糖蛋白分离纯化中的应用 23 第三章 糖蛋白理化性质检测和结构分析 34 第一节 糖蛋白的鉴定 34 第二节 糖蛋白的外观、溶解度、pH、水分及灰度测定 38 第三节 糖蛋白中糖含量、蛋白含量、分子量、纯度及等电点测定 38 第四节 糖蛋白糖肽键特征、单糖及氨基酸组分分析及摩尔比测定 42 第五节 糖蛋白的结构分析 43 第四章 中药糖蛋白类药物的生物活性 54 第一节 中药糖蛋白的抗肿瘤活性 54 第二节 中药糖蛋白的免疫调节作用 56 第三节 中药糖蛋白的抗氧化、抗衰老作用 61 第四节 中药糖蛋白的血脂调节作用 62 第五节 中药糖蛋白的降血糖作用 63 第六节 中药糖蛋白与细胞凋亡 64 第七节 中药糖蛋白的抗凝、抗血栓作用 65 第八节 中药糖蛋白对学习和记忆的影响 65 Contents Chapter One An Overview of TCM Glycoproteins 69 1 Significance of TCM Glycoprotein Studies 69 2 The Composition of TCM Glycoproteins 70 3 Metabolism of TCM Glycoproteins 79 4 The Biological Functions of TCM Glycoproteins 83 Chapter Two Techniques to Extract, Separate and Purify Glycoprotein from the Traditional Chinese Medicine 86 1 Techniques to Extract Glycoprotein from the Traditional Chinese Medicine (TCM) 87 2 Techniques to Separate and Purify Glycoprotein from TCM 90 3 The Application of Affinity Chromatography in the Separation and Purification of TCM Glycoproteins 94 4 The Application of Size Exclusion Chromatography in the Separation and Purification of TCM Glycoproteins 99 Chapter Three Physicochemical Characterization of Glycoprotein 112 1 Identification of Glycoprotein 112 2 Determination of the Morphology, Solubility, pH, Water and Ash Contents of the Glycoprotein 118 3 Determination of Carbohydrate Content, Protein Content, Molecular Weight, Purity and Isoelectric Point of Glycoprotein 119 4 Characteristics of Glycopeptide Bonds, Analysis of Monosaccharide and Amino Acid Component, and the Molar Ratio of Glycoprotein 124 5 Structural Analysis of Glycoprotein 126 Chapter Four Bioactivity of Glycoprotein in Traditional Chinese Medicines 140 1 Anticarcinoma Activity of Glycoprotein in Traditional Chinese Medicine 141 2 Immunomodulation Function of Glycoprotein of Traditional Chinese Medicines 143 3 Antioxidant and Anti-aging Effects of Glycoprotein of Traditional Chinese Medicine 150 4 Hypolipidemic Effect of Glycoprotein of Traditional Chinese Medicine 152 5 Hypoglycemic Effect of Glycoprotein of Traditional Chinese Medicine 153 6 Glycoprotein of Traditional Chinese Medicine and Apoptosis 154 7 Anticoagulant and Antithrombotic Effect of Glycoprotein of Traditional Chinese Medicine 155 8 Effect of Chinese Medicine Glycoprotein on Learning and Memory 156
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