目录
- Contents
Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v
Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ix
1 Synthesis and Characterization of Self-Assembled DNA Nanostructures . . . . . . . . 1
Chenxiang Lin, Yonggang Ke, Rahul Chhabra, Jaswinder Sharma,
Yan Liu, and Hao Yan
2 Protocols for Self-Assembly and Imaging of DNA Nanostructures . . . . . . . . . . . . 13
Thomas L. Sobey and Friedrich C. Simmel
3 Self-Assembly of Metal-DNA Triangles and DNA Nanotubes
with Synthetic Junctions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33
Hua Yang, Pik Kwan Lo, Christopher K. McLaughlin, Graham D. Hamblin,
Faisal A. Aldaye, and Hanadi F. Sleiman
4 DNA-Templated Pd Conductive Metallic Nanowires . . . . . . . . . . . . . . . . . . . . . . 49
Khoa Nguyen, Stephane Campidelli, and Arianna Filoramo
5 A Method to Map Spatiotemporal pH Changes Inside Living Cells Using a
pH-Triggered DNA Nanoswitch. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61
Souvik Modi and Yamuna Krishnan
6 Control of Helical Handedness in DNA and PNA Nanostructures . . . . . . . . . . . . 79
Roberto Corradini, Tullia Tedeschi, Stefano Sforza, Mark M. Green,
and Rosangela Marchelli
7 G-Quartet, G-Quadruplex, and G-Wire Regulated by Chemical Stimuli . . . . . . . . 93
Daisuke Miyoshi and Naoki Sugimoto
8 Preparation and Atomic Force Microscopy of Quadruplex DNA . . . . . . . . . . . . . . 105
James Vesenka
9 Synthesis of Long DNA-Based Nanowires. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115
Alexander Kotlyar
10 G-Wire Synthesis and Modification with Gold Nanoparticle . . . . . . . . . . . . . . . . . 141
Christian Leiterer, Andrea Csaki, and Wolfgang Fritzsche
11 Preparation of DNA Nanostructures with Repetitive Binding Motifs
by Rolling Circle Amplification . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 151
Edda Rei., Ralph H.lzel, and Frank F. Bier
12 Controlled Confinement of DNA at the Nanoscale: Nanofabrication and Surface
Bio-Functionalization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 169
Matteo Palma, Justin J. Abramson, Alon A. Gorodetsky, Colin Nuckolls,
Michael P. Sheetz, Shalom J. Wind, and James Hone
13 Templated Assembly of DNA Origami Gold Nanoparticle Arrays
on Lithographically Patterned Surfaces . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 187
Albert M. Hung and Jennifer N. Cha
14 DNA-Modified Single Crystal and Nanoporous Silicon. . . . . . . . . . . . . . . . . . . . . 199
Andrew Houlton, Bernard A. Connolly, Andrew R. Pike,
and Benjamin R. Horrocks
15 The Atomic Force Microscopy as a Lithographic Tool: Nanografting of DNA Nanostructures for Biosensing Applications . . . . . . . . . . . . . . . . . . . . . . . Matteo Castronovo and Denis Scaini 209
16 Trapping and Immobilization of DNA Molecules Between Nanoelectrodes. . . . . . Anton Kuzyk, J. Jussi Toppari, and P.ivi T.rm. 223
17 DNA Contour Length Measurements as a Tool for the Structural Analysis of DNA and Nucleoprotein Complexes. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Claudio Rivetti 235
18 DNA Molecular Handles for Single-Molecule Protein-Folding Studies by Optical Tweezers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Ciro Cecconi, Elizabeth A. Shank, Susan Marqusee, and Carlos Bustamante 255
19 Optimal Practices for Surface-Tethered Single Molecule Total Internal Reflection Fluorescence Resonance Energy Transfer Analysis. . . . . . . . . . . . . . . . . Matt V. Fagerburg and Sanford H. Leuba 273
20 Engineering Mononucleosomes for Single-Pair FRET Experiments. . . . . . . . . . . . Wiepke J.A. Koopmans, Ruth Buning, and John van Noort 291
21 Measuring DNA–Protein Binding Affinity on a Single Molecule Using Optical Tweezers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Micah J. McCauley and Mark C. Williams 305
22 Modeling Nanopores for Sequencing DNA. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Jeffrey R. Comer, David B. Wells, and Aleksei Aksimentiev 317
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 359
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