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生物化学,英文版,第2版BIOCHEMISTRY A Textbook for Medical Students
  • 书号:9787030453266
    作者:赵宝昌,关一夫
  • 外文书名:
  • 装帧:平装
    开本:16
  • 页数:382
    字数:913000
    语种:en
  • 出版社:科学出版社
    出版时间:2016-03-01
  • 所属分类:
  • 定价: ¥118.00元
    售价: ¥93.22元
  • 图书介质:
    纸质书

  • 购买数量: 件  可供
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本书是我国高等医学院校本科在华留学生和中、英双语教学的生物化学教科书,内容为医学专业类学生应该掌握的基础生物化学与分子生物学理论、基本知识和基本技能,同时也兼顾国家医师执业考试的要求。全书23章,内容分三个板块,分别包括蛋白质、核酸、维生素、酶和糖复合物的结构与功能;糖、脂、氨基酸、核苷酸和矿物质的代谢,以及生物氧化、血液和肝脏的代谢特点和代谢的整合与调节;DNA、RNA和蛋白质的生物合成、DNA损伤与修复、DNA技术、基因组学与蛋白质组学等组学,以及细胞信号转导和癌基因、肿瘤抑制基因和生长因子。全书共有插图342幅,表格67个。为了更好适应医学教学改革的需要,彰显医学生用生物化学教科书的医学专业特色,本书第二版增添了生物化学与医学联系的知识框70个,在分子水平上对某些临床医学现象进行解读。本书还特别注重在华留学生和双语教学的需要,重要的英文专业名词和术语均在其后标有相应的中文,并在书后附有名词释义,对重要的术语给出简洁、准确的概念。各章后均有中、英文对照小结。
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目录

  • Contents
    Introduction(1)
    Chapter 1 Structures and Functions of Proteins(4)
    1.1 Amino Acid Composition in Proteins(4)
    1.2 Molecular Structure of Proteins(7)
    1.3 Structure-Function Relationship of Proteins(13)
    1.4 Classification of Proteins(18)
    1.5 Protein Physicochemical Properties and Protein Exploration(18)
    Chapter 2 Structures and Functions of Nucleic Acids(27)
    2.1 Structural Units of Nucleic Acids—Nucleotides(27)
    2.2 Structures and Functions of DNA(29)
    2.3 Structures and Functions of RNA(34)
    2.4 Properties of Nucleic Acids(37)
    2.5 Nucleases(39)
    Chapter 3 Vitamins(41)
    3.1 Fat-soluble Vitamins(41)
    3.2 Water-soluble Vitamins(46)
    Chapter 4 Enzymes(53)
    4.1 Structure and Function of Enzymes(53)
    4.2 Properties and Catalytic Mechanisms of Enzymes(55)
    4.3 Kinetics of Enzyme-Catalyzed Reactions(58)
    4.4 Regulatory Enzymes(65)
    4.5 Nomenclature and Classification of Enzymes(67)
    4.6 Clinical Applications of Enzymes(68)
    Chapter 5 Glycoconjugates(72)
    5.1 Molecular Structures of Glycans(72)
    5.2 Structures and Functions of Glycoproteins(73)
    5.3 Structures and Functions of Proteoglycans(76)
    5.4 Structures and Functions of Glycolipids(78)
    Chapter 6 Biological Oxidation(82)
    6.1 Electron Transport Chain(82)
    6.2 Oxidative Phosphorylation(88)
    6.3 ATP and the Other High Energy Compounds(91)
    6.4 Selective Transport across the Inner Mitochondrial Membrane(92)
    6.5 Other Biological Oxidations(94)
    Chapter 7 Carbohydrate Metabolism(96)
    7.1 Digestion and Absorption of Carbohydrates(96)
    7.2 Anaerobic Degradation of Glucose(97)
    7.3 Aerobic Oxidation of Glucose(101)
    7.4 Pentose Phosphate Pathway(105)
    7.5 Glycogen Formation and Degradation(107)
    7.6 Gluconeogenesis(112)
    7.7 Blood Sugar and Its Regulation(115)
    Chapter 8 Lipid Metabolism(119)
    8.1 Fatty Acids and Derivatives of Polyunsaturated Fatty Acids(119)
    8.2 Digestion and Absorption of Lipids(122)
    8.3 Metabolism of Fats(123)
    8.4 Metabolism of Phospholipids(132)
    8.5 Metabolism of Cholesterol(135)
    8.6 Metabolism of Plasma Lipoproteins(137)
    Chapter 9 Protein Catabolism(146)
    9.1 Nutritional Roles of Dietary Proteins (146)
    9.2 Digestion, Absorption and Putrefaction of Dietary Proteins(147)
    9.3 Degradation of Protein in Cells(149)
    9.4 General Catabolism of Amino Acids(149)
    9.5 Metabolism of Ammonia(153)
    9.6 Individual Amino Acid Catabolism (156)
    Chapter 10 Nucleotide Metabolism (166)
    10.1 Biological and Medical Functions of Nucleotides(166)
    10.2 Degradation of Nucleic Acids (166)
    10.3 Metabolism of Purine Nucleotides(167)
    10.4 Metabolism of Pyrimidine Nucleotides(171)
    10.5 Deoxyribonucleotide Biosynthesis(173)
    10.6 Biosynthesis of Nucleoside Diphosphate and Nucleoside Triphosphate(174)
    10.7 Dysmetabolism of Nucleotides and Antimetabolites(175)
    Chapter 11 Blood Biochemistry(178)
    11.1 Plasma Proteins(178)
    11.2 Structure and Function of Albumin(181)
    11.3 Synthesis of Hemoglobin and Its Regulation(182)
    11.4 Metabolism of Blood Cells(185)
    Chapter 12 Liver Biochemistry(190)
    12.1 The Role of Liver in Material Metabolism(190)
    12.2 Hepatic Biotransformation(192)
    12.3 Metabolism of Bile Acid(197)
    12.4 Bile Pigment Metabolism and Jaundice(201)
    Chapter 13 Mineral Biochemistry(207)
    13.1 Calcium, Phosphorus, and Magnesium Metabolism(207)
    13.2 Trace Elements(210)
    Chapter 14 Integration and Regulation of Metabolism(214)
    14.1 Common Characteristics of Metabolism(214)
    14.2 Interconnections of Metabolism(215)
    14.3 Metabolic Specializations of Some Organs(217)
    14.4 Regulatory Strategy of Metabolism(219)
    Chapter 15 DNA Biosynthesis(229)
    15.1 General Features of DNA Replication (229)
    15.2 Enzymology and Topology of DNA Replication (231)
    15.3 Replication of Prokaryotic Systems(235)
    15.4 Replication of Eukaryotic Systems(237)
    15.5 Reverse Transcription and Other Modes of DNA Replication(240)
    Chapter 16 DNA Damage and Repair(243)
    16.1 DNA Damage(243)
    16.2 Repair of DNA Damage(245)
    16.3 Significance of DNA Damage and Repair to DNA Damage(248)
    Chapter 17RNA Biosynthesis and Processing(250)
    17.1 Overview of Transcription(250)
    17.2 Transcription in Prokaryotes(252)
    17.3 Transcription in Eukaryotes(256)
    17.4 Processing of Eukaryotic RNAs(261)
    Chapter 18 Protein Biosynthesis, Modification and Targeting(269)
    18.1 Machinery Involved in Translation(269)
    18.2 Amino Acid Activation(273)
    18.3 Protein Biosynthesis Journey(274)
    18.4 Protein Posttranslational Modifications and Targeting(281)
    18.5 Clinical Correlation of Protein Biosynthesis(286)
    Chapter 19 Regulation of Gene Expression (289)
    19.1 General Characteristics of Gene Expression(289)
    19.2 Regulation of Gene Expression in Prokaryotes(291)
    19.3 Regulation of Gene Expression in Eukaryotes(296)
    Chapter 20 DNA Technologies(303)
    20.1 Molecular Hybridization(303)
    20.2 DNA Sequencing(305)
    20.3 Polymerase Chain Reaction(306)
    20.4 Recombinant DNA Technology (311)
    20.5 Transgenesis and Gene Targeting(316)
    20.6 Gene Diagnosis and Gene Therapy(317)
    Chapter 21Signal Transduction(323)
    21.1 Signal Molecules(323)
    21.2 Receptors(324)
    21.3 Signal Transduction Pathways(328)
    21.4 Signal Transduction Network(340)
    21.5 Signal Transduction and Medicine(340)
    Chapter 22 Oncogenes, Tumor Suppressor Genes and Growth Factors(343)
    22.1 Oncogenes(343)
    22.2 Tumor Suppressor Genes(347)
    22.3 Growth Factors(350)
    Chapter 23 Genomics, Proteomics, and Other Omics(353)
    23.1 Genomics(353)
    23.2 Proteomics(355)
    23.3 Other Omics(357)
    23.4 Omics and Medicine(358)
    The Major References(360)
    Index(361)
    Glossary(369)
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